J Interdiscip Dentistry
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Year : 2020  |  Volume : 10  |  Issue : 2  |  Page : 67-73

The comparative evaluation of the effects of antioxidants pretreatment on remineralization of demineralized dentin - In vitro study

Department of Conservative Dentistry and Endodontics, CSMSS Dental College, Aurangabad, Maharashtra, India

Correspondence Address:
Dr. Kalyani S Kagne
Department of Conservative Dentistry and Endodontics, CSMSS Dental College, Aurangabad, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jid.jid_10_20

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Context: Mechanical performance of dentin is of significant significance for the overall function of the teeth. Remineralization of carious dentin is the ultimate goal in re-establishing the functionality of the affected tissue to regain and maintain the mechanical properties of dentin. Functional remineralization of the affected dentin involves stabilization of both inorganic and organic component, but remineralizing agents stabilize only inorganic content. Hence, to stabilize organic content and to bring in functional remineralization, the use of anti-collagenolytic and anti-elastastic agents was considered for this study. Aims: The aim is to assess and compare the effect of antioxidants pretreatment on remineralization of demineralized dentin-in vitro study. Settings and Design: Experimental randomized analytical- in vitro study. Subjects and Methods: Ninety specimens were subjected to artificial caries lesions and were randomly divided into six groups based on the pretreatment with white tea, and grape seed extract (GSE) followed by casein phosphopeptide amorphous calcium phosphate and casein phosphopeptide amorphous calcium phosphate with fluoride. All the specimens were subjected to pH cycling regimen. The specimens were subjected to Vickers micro-hardness test to obtain the micro-hardness values. Statistical Analysis Used: The values were statistically analyzed using one-way analysis of variance. Results: After pH cycling, GSE showed a significant increase in micro-hardness values (46.57 ± 3.51 VHN), followed by white tea (42.56 ± 5.20) with the level of significance <0.05. Conclusions: Results of this study showed that naturally occurring antioxidants, i.e., 10% White tea and 6.5% GSE can be used as pretreatment regime before remineralization treatment.

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