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| LETTER TO EDITOR |
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| Year : 2018 | Volume
: 8
| Issue : 1 | Page : 41 |
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Refractory Mucormycosis: A Possible Cause for Maxillary Necrosis
Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
| Date of Web Publication | 5-Mar-2018 |
Correspondence Address:
Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, P. O. Box: 55302, Baghdad Post Office, Baghdad
Iraq
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jid.jid_96_17
How to cite this article:
Al-Mendalawi MD. Refractory Mucormycosis: A Possible Cause for Maxillary Necrosis. J Interdiscip Dentistry 2018;8:41 |
Sir,
I read with interest the case report by Arora et al. on the refractory mucormycosis resulting in maxillary necrosis in an Indian patient.[1] It is obvious that mucormycosis often occurs in immunocompromised individuals. Although the studied patient was immunodeficient by the underlying diabetes mellitus and hypothyroidism, I presume that the following immunodeficient condition ought to be concomitantly considered in the studied patient. Due to impaired immunity, individuals with human immunodeficiency virus (HIV) infection are susceptible to opportunistic infections more than individuals with a healthy immune system. Among these infections, mucormycosis has been reported in HIV-positive patients that has significant morbidity and mortality.[2] To my knowledge, HIV infection is a worrisome health issue in India. The current national HIV prevalence is 0.26% compared with a global average of 0.2%.[3] I presume that the rare occurrence of oral mucormycosis should alert the authors to define the HIV status of the studied patient. Hence, the arrangement for the diagnostic algorithm of CD4 count and viral overload measurements was solicited. If that diagnostic algorithm was done and it revealed underlying HIV infection, the case in question could be confidently considered a novel case report in India as HIV-associated maxillary mucormycosis has been rarely reported in the literature.[4]
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
 References | |  |
| 1. | Arora A, Patil BA, Adepu A, Reynold R. Refractory mucormycosis: A possible cause for maxillary necrosis. J Interdiscip Dent 2017;7:65-8.  |
| 2. | Moreira J, Varon A, Galhardo MC, Santos F, Lyra M, Castro R, et al. The burden of mucormycosis in HIV-infected patients: A systematic review. J Infect 2016;73:181-8. |
| 3. | Paranjape RS, Challacombe SJ. HIV/AIDS in India: An overview of the Indian epidemic. Oral Dis 2016;22 Suppl 1:10-4. |
| 4. | Pedro-de-Lelis FJ, Sabater-Marco V, Herrera-Ballester A. Necrotizing maxillary sinus mucormycosis related to candidiasis and microsporidiosis in an AIDS patient. AIDS 1995;9:1386-8. |
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