J Interdiscip Dentistry
Home | About JID | Editors | Search | Ahead of print | Current Issue | Archives | Instructions |
Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 273  | Login  | Contact us | Advertise | Subscribe  
Year : 2018  |  Volume : 8  |  Issue : 1  |  Page : 18-22

Royal Jelly Antimicrobial Activity against Periodontopathic Bacteria

Department of Periodontics, Bapuji Dental College, Davangere, Karnataka, India

Correspondence Address:
Sowmya Nagur Karibasappa
Bapuji Dental College, Davangere, Karnataka
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jid.jid_72_17

Rights and Permissions

Background: Royal jelly (RJ) is a milky white highly viscous secretion from the salivary gland of the worker hive bees. RJ is a nutritive secretion that acts as biocatalyst in cell regeneration processes within the human body and exhibits antimicrobial effects. Materials and Methods: RJ antimicrobial activity against periodontopathic (American type cell culture) bacteria was investigated “in vitro.” Bacterial strains tested were Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi), and Fusobacterium nucleatum (Fn). Minimum inhibitory concentration for the strains tested was determined using the method of broth dilution with the RJ sample in serial concentrations. Results: The minimum bactericidal concentration values were identical and showed bactericidal effect in the range between 12.5 and 100 μg/ml, suggesting that periodontal pathogens tested were susceptible to RJ. Conclusion: Results showed that the inhibitory effects on Pg and Pi at different concentrations demonstrated concurrent similarity, whereas higher concentrations were necessary to inhibit the growth of Aa and Fn. However, the requirement for a standardized method for quality evaluation of RJ, i.e., qualitative, quantitative, and biological activity is a necessity, and its dosage and safety must be tested before its possible in vivo application.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded477    
    Comments [Add]    
    Cited by others 6    

Recommend this journal