J Interdiscip Dentistry
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Year : 2013  |  Volume : 3  |  Issue : 2  |  Page : 71-78

Role of probiotics on oral health: A randomized, double-blind, placebo-controlled study

1 Department of Conservative Dentistry, MM College of Dental Sciences and Research, Mullana, Ambala, Haryana, India
2 Department of Perioidontology, MM College of Dental Sciences and Research, Mullana, Ambala, Haryana, India

Correspondence Address:
Rajan Dhawan
Department of Conservative Dentistry, MM College of Dental Sciences and Research, Mullana, Ambala, Haryana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-5194.126862

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Aim: The aim of this study was to investigate commercially available combined probiotic formulation for its effect on plaque, gingivitis, and salivary Streptococcus mutans levels in subjects with chronic gingivitis. Materials and Methods: A total of 36 subjects were finally enrolled in a double-blind, placebo-controlled, randomized trial. Selected subjects were randomly divided into two groups: Group A (control group) with 17 subjects receiving placebo tablets twice daily and Group B (probiotic group) with 19 subjects receiving probiotic tablets twice daily. The study consisted of two 2-week periods: a 2-week intervention period (T1-T2) and a 2-week posttreatment period (T2-T3). Clinical parameters and bacterial counts of salivary Streptococcus. mutans were evaluated at baseline (T1), at the completion (T2) of medication, and 2 weeks after the medication (T3). Results: On comparative evaluation between the two groups, results indicated that Group B (probiotic group) exhibited statistically significant reduction in Plaque Index, Gingival Index, Calculus Index and Streptococcus. mutans level than Group A (control group) over the entire span of the study. Conclusion: Our results indicated that probiotic could be useful in the improvement/maintenance of oral health. Clinical Relevance to Interdisciplinary Dentistry
  • If left untreated, gingivitis can progress, increasing the risk of tooth loss. Oral administration of probiotics benefits oral health by preventing the growth of harmful microbiota or by modulating mucosal immunity in the oral cavity.
  • In this study, probiotics were given orally for 2 weeks to subjects suffering from gingivitis and results showed improvement in oral health.
  • Bacteriotherapy in the form of probiotics seems to be a natural way to maintain health and protect oral tissues from disease.
  • Efforts have been made in this article to increase the awareness with this aspect of oral disease therapy and encourage the implementation of the concept of "food rather than medicine".

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